FORMULATION, DEVELOPMENT AND EVALUATION OF LAMIVUDINE ENCAPSULATED SOLID LIPID NANOPARTICLES
نویسندگان
چکیده
منابع مشابه
Formulation and Evaluation of Solid Lipid Nanoparticles of Ramipril
Solid lipid nanoparticles are typically spherical with an average diameter between 1 and 1000 nm. It is an alternative carrier system to tradition colloidal carriers, such as, emulsions, liposomes, and polymeric micro and nanoparticles. Ramipril is an antihypertensive agent used in the treatment of hypertension. Its oral bioavailability is 28% and it is rapidly excreted through the renal route....
متن کاملFormulation and Evaluation of Solid lipid nanoparticles: Isoniazid
Tuberculosis is an infectious disease caused by Mycobacterium Tuberculosis which attacks lungs and other parts of the body. Isoniazid is a hydrophilic drug that is having a first line antituberculosis drug. Entrapment Efficiency has been improved by preparing Solid Lipid Nanoparticles (SLNs). Two different variable Stearic acid and Tween 80 were used by using w/o/w double emulsion-solvent evapo...
متن کاملFormulation & Evaluation of Gemcitabine Hydrochloride Loaded Solid Lipid Nanoparticles
INTRODUCTION Gemcitabine hydrochloride is an antimetabolite (pyrimidine analog) with poor oral bioavailability (9%) due to the first pass metabolism. GEM is a water soluble drug (log p = -1.4) with a short half-life of 42 to 94 minutes (short infusions) and 245 to 638 minutes (long infusions) respectively. Extensive first pass metabolism, low bioavailability, high dosing frequency and less half...
متن کاملSimvastatin Solid Lipid Nanoparticles for Oral Delivery: Formulation Development and In vivo Evaluation
Solid lipid nanoparticles have been increasingly utilised for improving oral bioavailability of drugs. Simvastatin is biopharmaceutical class 2 drug with poor oral bioavailability of 5%. In the present study, simvastatin solid lipid nanoparticles were successfully prepared by hot melt emulsification process and optimised with respect to surfactant and lipid concentration, and drug loading. The ...
متن کاملPreparation, characterization and evaluation of Ginkgo biloba solid lipid nanoparticles
Objective(s): In this work, Ginkgo biloba extract (GBE) loaded solid lipid nanoparticles (SLNs) were synthesized via high pressure homogenization method and their physicochemical properties, as well as cytotoxicity and antibacterial activities were evaluated.Methods: Ginkgo biloba extract SLNs (GBE-SLNs) were prepared using high pressure homogenization method. The morphology and size of S...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Asian Journal of Pharmaceutical Education and Research
سال: 2021
ISSN: 2278-7496
DOI: 10.38164/ajper/10.1.2021.64-77